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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA0664
All Species:
18.48
Human Site:
S274
Identified Species:
33.89
UniProt:
O75153
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75153
NP_056044.3
1309
146670
S274
H
F
N
P
K
P
A
S
P
R
F
L
S
H
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548323
1501
166268
S466
H
F
N
P
K
P
A
S
P
R
F
L
S
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5SW19
1315
148050
S274
H
F
N
P
K
P
A
S
P
R
F
L
S
H
S
Rat
Rattus norvegicus
XP_001080615
1352
151608
S315
H
F
N
P
K
P
A
S
P
R
F
L
S
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509391
982
108607
I69
P
Q
E
M
V
Q
E
I
H
Q
V
L
M
D
R
Chicken
Gallus gallus
XP_415920
1293
145294
N310
N
F
N
P
K
P
A
N
P
S
F
L
S
H
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A0JMD0
1400
155792
N319
N
F
S
P
K
P
A
N
P
S
F
L
S
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZAB5
1448
160833
N363
T
F
N
P
K
P
D
N
P
S
H
L
S
H
S
Honey Bee
Apis mellifera
XP_624898
1290
145677
T295
V
F
N
P
K
P
A
T
P
S
H
L
C
H
S
Nematode Worm
Caenorhab. elegans
P34466
1247
139903
N268
R
F
D
P
T
V
S
N
S
N
K
T
V
Y
Q
Sea Urchin
Strong. purpuratus
XP_001198284
1101
124381
S189
Y
N
G
V
D
C
Q
S
L
S
F
L
S
T
V
Poplar Tree
Populus trichocarpa
XP_002314020
1343
146561
L267
F
E
N
V
Q
S
L
L
P
P
C
S
W
L
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RY84
1211
135142
P248
P
S
A
P
W
L
V
P
S
I
N
S
S
L
I
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
83.3
N.A.
94.9
89.9
N.A.
60.8
83.1
N.A.
75
N.A.
52
59.8
39.9
51.9
Protein Similarity:
100
N.A.
N.A.
85.5
N.A.
96.9
92.7
N.A.
67.2
89.3
N.A.
83.6
N.A.
69
75.7
59.5
63.7
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
6.6
80
N.A.
73.3
N.A.
66.6
66.6
13.3
26.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
13.3
93.3
N.A.
93.3
N.A.
73.3
73.3
40
33.3
Percent
Protein Identity:
27.3
N.A.
N.A.
N.A.
N.A.
29
Protein Similarity:
46.6
N.A.
N.A.
N.A.
N.A.
48.9
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
54
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
8
0
8
0
0
% C
% Asp:
0
0
8
0
8
0
8
0
0
0
0
0
0
8
0
% D
% Glu:
0
8
8
0
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
8
70
0
0
0
0
0
0
0
0
54
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
31
0
0
0
0
0
0
0
8
0
16
0
0
62
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
8
% I
% Lys:
0
0
0
0
62
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
8
8
8
0
0
77
0
16
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
16
8
62
0
0
0
0
31
0
8
8
0
0
0
0
% N
% Pro:
16
0
0
77
0
62
0
8
70
8
0
0
0
0
0
% P
% Gln:
0
8
0
0
8
8
8
0
0
8
0
0
0
0
8
% Q
% Arg:
8
0
0
0
0
0
0
0
0
31
0
0
0
0
8
% R
% Ser:
0
8
8
0
0
8
8
39
16
39
0
16
70
0
62
% S
% Thr:
8
0
0
0
8
0
0
8
0
0
0
8
0
8
0
% T
% Val:
8
0
0
16
8
8
8
0
0
0
8
0
8
0
8
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _